HKU-BAL/Clair

ONT R9.4.1 vs R10.3

fidibidi opened this issue · 1 comments

Hello!

Clair3 has been working great, and thank you guys for sharing such solid tech.

This is mainly a question, but:

I've processed a few PromethION and minION samples through clair3, but those were run using R9.4.1.
My team is interested in ONT tech, and want to try it out, but will likely use their newer flowcells the R10.3.

Based on this, is it a bad idea to continue using the existing ONT models in Clair3 to do variant calling? Or would creating a new model trained with these flowcells be the correct step?

My apologies, this is in the wrong repo!