/striatum_imaging_natureneuro

This is the repository that goes along with Gritton et al. (2019), "Unique contributions of parvalbumin and cholinergic interneurons in organizing striatal networks during movement"

Primary LanguageMATLAB

striatum_imaging_natureneuro

This is the repository that goes along with Gritton et al. (2019), "Unique contributions of parvalbumin and cholinergic interneurons in organizing striatal networks during movement"

Processing

Please use processFastManual in order to process videos as per our final processing routine. For tdTomato images, we used a simpler processing scheme "processTDT". We then tagged ROIs using one of the selectSingleFrameROIs*.m, and identified using the tdTomato images which of the ROIs corresponded to tdTomato-positive cells. To extract traces, use processROIs for the non-opto data or processROIsLaser for the opto data.

Post-processing

At this point, we went through our extracted traces, identified which were dynamic and broad (described in the paper), and went forward with the analysis. loadAndFormatPreInfusion* (2 for non-opto data, 3 for opto data) were used to condense and interpolate the traces.

Data analysis

For the final data analysis, refer to the script main_110718 for the generation of each figure.