HeliXonProtein/binding-ddg-predictor

how binding-ddg-predictor calculate ddg?

biotech70 opened this issue · 2 comments

Hi, which one of the following formulae use in binding-ddg-predictor for ddg calculation?
1- ddg = dg/mutant - dg/wild
or
2- ddg = dg/wild - dg/mutant

I need your help since I can't find any tutorial about your tools and the method of ddg calculation.

Hi,

We used ddg = dg/mutant - dg/wild.