Which genes does arcasHLA support?
slowkow opened this issue · 1 comments
slowkow commented
IMGTHLA/alignments release 3.49.0 includes:
A,B,C,DMA,DMB,DOA,DOB,DPA1,DPB1,DQA1,DQA2,DQB1,DRA,DRB,E,F,G,HFE,MICA,MICB,TAP1,TAP2
Can we genotype all of these genes with arcasHLA by using the following command?
arcasHLA genotype R1.fq.gz R2.fq.gz -g A,B,C,DMA,DMB,DOA,DOB,DPA1,DPB1,DQA1,DQA2,DQB1,DRA,DRB,E,F,G,HFE,MICA,MICB,TAP1,TAP2
Or are we limited only to these genes?
A,B,C,DPB1,DQB1,DQA1,DRB1
olekskrav commented
Hi Kamil. Thank you for your interest in our tool. The choice of genes is limited to the ones listed in the file dat/info/parameters.json
, which are currently as follows:
A,B,C,DMA,DMB,DOA,DOB,DPA1,DPB1,DQA1,DQB1,DRA,DRB1,DRB3,DRB5,E,F,G,H,J,K,L
If you do not supply the -g/--genes
argument, all these genes will be considered by default.
We are planning to add the missing genes in a future release. (Similar issues: #60, #56, #38, #15.)