Is it possible to use a predicted antibody structure to initialize X_i^(0)?

[semal]

Excellent work, and very thx for open source. This is my question.
If Using tools like Igfold or alphafold to predict antibody, then use this structure to initialize X. Of course for the [MASK] residue using a random residue to replace when using the predict tools. Have you try something like this?

[kxz18]

Hi, I didn't try that. To do that, maybe we need to train a new model. However, if you're using Igfold to predict the structure, I think directly letting dyMEAN to do the structure prediction might achieve similar or even better performance, as compared in the paper.