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H&E-to-IHC Stain Translation
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gradio
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app.py
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H&E-to-IHC Stain Translation

Gradio App based on Adaptive Supervised PatchNCE Loss for Learning H&E-to-IHC Stain Translation with Inconsistent Groundtruth Image Pairs (MICCAI 2023)

Online demo: Hugging Face Spaces

Original folder: lifangda01/AdaptiveSupervisedPatchNCE

Original paper: arXiv

🎯 Overview

This repository features a Gradio-based application built on the methods introduced in the MICCAI 2023 paper, "Adaptive Supervised PatchNCE Loss for Learning H&E-to-IHC Stain Translation with Inconsistent Groundtruth Image Pairs." The application facilitates automatic virtual staining, transforming H&E (Hematoxylin and Eosin) images into corresponding IHC (ImmunoHistoChemistry) images.

Users can generate virtual IHC stains for four key biomarkers critical to breast cancer diagnostics:

  • HER2: Human Epidermal Growth Factor Receptor 2
  • ER: Estrogen Receptor
  • Ki67: Antigen KI-67 (cell proliferation marker)
  • PR: Progesterone Receptor

This tool simplifies and accelerates the analysis of histopathological samples, making advanced diagnostic insights more accessible through virtual staining technology.

Input H&E Image Output IHC Image (Ki67)