HttpBadRequest when using assay_type__iregex

[jonjoncardoso]

Hi!

I am facing an error whenever I try to filter assay types. I thought it was something related to v0.10.7 but I downgraded to v0.10.5 and it persists.

This error can be reproduced with example 30 from the README:

from chembl_webresource_client.new_client import new_client
activity = new_client.activity
res = activity.filter(target_chembl_id='CHEMBL3938', assay_type__iregex='(B|F)')

which throws:

---------------------------------------------------------------------------
HttpBadRequest                            Traceback (most recent call last)
/opt/conda/lib/python3.9/site-packages/IPython/core/formatters.py in __call__(self, obj)
    700                 type_pprinters=self.type_printers,
    701                 deferred_pprinters=self.deferred_printers)
--> 702             printer.pretty(obj)
    703             printer.flush()
    704             return stream.getvalue()

/opt/conda/lib/python3.9/site-packages/IPython/lib/pretty.py in pretty(self, obj)
    392                         if cls is not object \
    393                                 and callable(cls.__dict__.get('__repr__')):
--> 394                             return _repr_pprint(obj, self, cycle)
    395 
    396             return _default_pprint(obj, self, cycle)

/opt/conda/lib/python3.9/site-packages/IPython/lib/pretty.py in _repr_pprint(obj, p, cycle)
    698     """A pprint that just redirects to the normal repr function."""
    699     # Find newlines and replace them with p.break_()
--> 700     output = repr(obj)
    701     lines = output.splitlines()
    702     with p.group():

/opt/conda/lib/python3.9/site-packages/chembl_webresource_client/query_set.py in __repr__(self)
     76             return '{0} resource'.format(self.model.name)
     77         clone = self._clone()
---> 78         data = list(clone[:Settings.Instance().REPR_OUTPUT_SIZE])
     79         length = len(self)
     80         if length > Settings.Instance().REPR_OUTPUT_SIZE:

/opt/conda/lib/python3.9/site-packages/chembl_webresource_client/query_set.py in __next__(self)
    125 
    126     def __next__(self):
--> 127         return self.next()
    128 
    129 #-----------------------------------------------------------------------------------------------------------------------

/opt/conda/lib/python3.9/site-packages/chembl_webresource_client/query_set.py in next(self)
    111             return None
    112         if not self.chunk and not self.current_index:
--> 113             self.chunk = self.query.get_page()
    114         if not self.chunk or self.current_index >= len(self.chunk):
    115             self.chunk = self.query.next_page()

/opt/conda/lib/python3.9/site-packages/chembl_webresource_client/url_query.py in get_page(self)
    394             self.logger.info('From cache: {0}'.format(res.from_cache if hasattr(res, 'from_cache') else False))
    395             if not res.ok:
--> 396                 handle_http_error(res)
    397             if self.frmt == 'json':
    398                 json_data = res.json()

/opt/conda/lib/python3.9/site-packages/chembl_webresource_client/http_errors.py in handle_http_error(request)
    111         exception_class = status_to_exception.get(request.status_code, BaseHttpException)
    112         if request.text:
--> 113             raise exception_class(request.url, request.text)
    114         raise exception_class(request.url, request.content)
    115 

HttpBadRequest: Error for url https://www.ebi.ac.uk/chembl/api/data/activity.json, server response: {"error_message": "'iregex' is not an allowed filter on the 'assay_type' field."}

[chrisdid4]

I have the same issue. Does someone knows a solution please?

[chrisdid4]

In my case I replaced the assay_type__iregex='(B|F)' with assay_type='B' and it worked

[juanfmx2]

Unfortunately, the regex filters on the activity endpoint had to be disabled because they did not perform very well, and they we making the web services unresponsive. The best alternative is to create 2 separate requests:
assay_type='B' and assay_type='F'