annotations can not be saved

[MinfanZhao]

I use ASAP 1.8.1 and ASAP 1.9 to annotate the images ( type of .mrxs), but i can't save the annotations.
The OS is windows 10, and i tried to run as administrator but can't solve this problem.
Besides, when i use ASAP1.8.1 installed in another PC before, the annotations can be saved correctly.

update:
I can save it in desktop but can't save in disk D.
( so strange.