Skin proposed new cell ontology terms
olgabot opened this issue · 0 comments
Hello!
This discussion is to propose the free_annotation
terms to the Cell Ontology so that future researchers may use your specific terms rather than the generic ones that you had to use. Below are your free_annotation
terms and what I (@olgabot) thought the relationship was to the existing cell ontology term, whether it was brand new term and cell type, in which case I used is_a
, or it was merely a synonym for a term that already existed in the cell ontology, in which case I used synonym
.
Please comment below with what is the correct relationship between terms, or correct the term itself and I'll deal with the submission to the Cell Ontology group.
Thank you for your help!
Warmest,
Olga
For the annotations below, here is the format:
- free annotation
relationship
cell ontology class
Relationships could be either:
is_a
- means that the free annotation label is a new "cell type" to add to the cell ontologysynonym
- means that the free annotation label is not a new cell type, but another term for the same thing that already exists in the cell ontology
I wasn't always sure which relationship to use so please comment below and I will correct it.
Examples:
- Inhibitory neuron
is_a
neuron - alveolar epithelial type 2 cells
synonym
type II pneumocyte
FACS and droplet free annotation tables in the "Details" below.
FACS free annotation table
tissue | cell_ontology_class | free_annotation | n_cells |
---|---|---|---|
Skin | basal cell of epidermis | Basal IFE | 562 |
Skin | epidermal cell | Intermediate IFE | 276 |
Skin | keratinocyte stem cell | Inner Bulge | 573 |
Skin | keratinocyte stem cell | Outer Bulge | 831 |
Skin | leukocyte | Leukocyte | 15 |
Skin | stem cell of epidermis | Replicating Basal IFE | 53 |
Droplet free annotation table
tissue | cell_ontology_class | free_annotation | n_cells |
---|
Proposed annotations
FACS
- basal skin interfollicular epidermis cell
is_a
basal cell of epidermis - intermediate skin interfollicular epidermis cell
is_a
epidermal cell - inner bulge cell
is_a
keratinocyte stem cell - replicating basal interfollicular epidermis cell
is_a
stem cell of epidermis