How can we use RPKM or TPM values for prediction of CNVs or tumour cells?

[avln24]

Hello @diazlab and @soerenmueller

I want to apply CONICSmat to a gene expression matrix of rpkm values and a matrix of tpm values.
How should I go about converting rpkm or tpm to log2(cpm/10+1) values so that I may apply CONICSmat?

Thank you