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Multifocal visual evoked potentials for quantifying optic nerve dysfunction in patients with optic disc drusen

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Paper

Link: https://onlinelibrary.wiley.com/doi/full/10.1111/aos.13347
Year: 2017

Summary

To explore the applicability of multifocal visual evoked potentials (mfVEPs) for research and clinical diagnosis in patients with optic disc drusen (ODD). This is the first assessment of mfVEP amplitude in patients with ODD.

  • mfVEP represents local responses from multiple visual inputs providing spatial information more sensitive to localized defects
  • mfVEPs can overcome most of the limitations of conventional VEPs, allowing simultaneous recording of local responses from many regions of the visual field with high spatial resolution.
  • mfVEP technique has been shown to be more sensitive than standard automated perimetry

Methods

  • cortically scaled 56‐segment dartboard pattern with 16 checks alternating between black and white in each segment
  • viewing distance of 30 cm from the screen

Results

  • segmenting the visual field in different segments proved useful to discriminate between ODD patients and control subjects
  • segmenting the visual field in areas (rings, quadrants, etc.) had the ability to uncover these defects