awesome spatial omics

review papers

tutorial

methods

In situ polyadenylation enables spatial mapping of the total transcriptome

tools

  • DestVI identifies continuums of cell types in spatial transcriptomics data. DestVI is available as part of the open-source software package scvi-tools (https://scvi-tools.org).
  • SpaGene: Scalable and model-free detection of spatial patterns and colocalization
  • Palo: Spatially-aware color palette optimization for single-cell and spatial data
  • squidpy paper - code: Squidpy: a scalable framework for spatial omics analysis
  • ncem paper - code: Learning cell communication from spatial graphs of cells
  • Spatially informed cell-type deconvolution for spatial transcriptomics Here, we introduce a deconvolution method, conditional autoregressive-based deconvolution (CARD), that combines cell-type-specific expression information from single-cell RNA sequencing (scRNA-seq) with correlation in cell-type composition across tissue locations. https://github.com/YingMa0107/CARD
  • Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace
  • SpatialCorr: Identifying Gene Sets with Spatially Varying Correlation Structure
  • RCTD: Robust decomposition of cell type mixtures in spatial transcriptomics
  • Supervised spatial inference of dissociated single-cell data with SageNet: a graph neural network approach that spatially reconstructs dissociated single cell data using one or more spatial references. code