Look for other our projects at https://github.com/RNA-Puzzles
Please Cite:
M. Magnus, M. Antczak, T. Zok, J. Wiedemann, P. Lukasiak, Y. Cao, Y. Cao, J. M. Bujnicki, E. Westhof, M. Szachniuk, and Z. Miao, “RNA-Puzzles toolkit: a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools.,” Nucleic Acids Research, vol. 224, p. 759, Dec. 2019.
Curated structures submitted to the RNA-Puzzles experiment, processed semi-manually by @mmagnus and with https://github.com/mmagnus/rna-tools and the community.
The RNA Puzzles:
- Puzzle 1: RNA dimer of a regulatory element from human thymidylate synthase mRNA
- Puzzle 2: Self-assembling RNA square
- Puzzle 3: Glycine riboswitch
- Puzzle 4: SAM-I riboswitch aptamer
- Puzzle 5: Lariat capping ribozyme.
- Puzzle 6: Adenosylcobalamin riboswitch
- Puzzle 7: Varkud satellite ribozyme
- Puzzle 8: SAM riboswitch
- Puzzle 9: 5-hydroxytryptophan aptamer
- Puzzle 10: T-box riboswitch and tRNA
- Puzzle 11: 5′-terminal hairpin of the 7SK snRNA
- Puzzle 12: YdaO riboswitch
- Puzzle 13: ZMP riboswitch
- Puzzle 14: L-glutamine riboswitch (Free) & L-glutamine riboswitch (Bound)
- Puzzle 15: Hammerhead
- Puzzle 16: TBA
- Puzzle 17: Pistol ribozyme
- Puzzle 18: Zika virus
- Puzzle 19: Twister sister
- Puzzle 20: Twister Sister ribozyme
- Puzzle 21: Guanidine III riboswitch
- Puzzle 24: Adenovirus virus-associated RNA
Predictions with ligands (see files in subfolder "raw" of given Puzzle):
- Puzzle 4: SAM-I riboswitch aptamer (Das only)
- Puzzle 9: 5-hydroxytryptophan aptamer (Bujnicki only)
- Puzzle 13: ZMP riboswitch (Das only)
- Puzzle 21: Guanidine III riboswitch (Adamiak, Chen, Das, Sanbonmatsu)
CASP15:
- R1107 human CPEB3 HDV-like ribozyme (PDB ID: 7QR4, 7QR3)
- R1116 Cloverleaf RNA, Poliovirus
Please Cite:
M. Magnus, M. Antczak, T. Zok, J. Wiedemann, P. Lukasiak, Y. Cao, Y. Cao, J. M. Bujnicki, E. Westhof, M. Szachniuk, and Z. Miao, “RNA-Puzzles toolkit: a computational resource of RNA 3D structure benchmark datasets, structure manipulation, and evaluation tools.,” Nucleic Acids Research, vol. 224, p. 759, Dec. 2019.
Download a zip file https://github.com/mmagnus/RNA-Puzzles-Standardized-Submissions/archive/master.zip
Used in:
[1] T. Zhang, G. Hu, Y. Yang, J. Wang, and Y. Zhou, “All-Atom Knowledge-Based Potential for RNA Structure Discrimination Based on the Distance-Scaled Finite Ideal-Gas Reference State,” J. Comput. Biol., pp. cmb.2019.0251–12, Oct. 2019.
[2] Li, J., Zhu, W., Wang, J., Li, W., Gong, S., Zhang, J., & Wang, W. (2018). RNA3DCNN: Local and global quality assessments of RNA 3D structures using 3D deep convolutional neural networks. PLoS Computational Biology, 14(11), e1006514. http://doi.org/10.1371/journal.pcbi.1006514