nf-core/scdownstream

Implement methods for ambient RNA removal

nictru opened this issue · 1 comments

Description of feature

decontX has already been implemented. The following methods also look interesting:

Tasks

  1. enhancement
  2. enhancement
  3. enhancement
grst commented

There's also scAR which is a newer, autoencoder-based method.

Here's a benchmark paper that recommends cellbender, but also argues that most downstream tasks do not benefit from ambient RNA removal (except for manual cell-type annotation).