Questions about using R packages GRaNIE

[aaaaaaaaaayong]

Hello,
I hope this message finds you well. I wanted to reach out to you regarding the use of your remarkable R package, GRaNIE. I have recently obtained pan-cancer bulk RNA-seq and ATAC-seq datasets, both of which have the potential to greatly benefit from the capabilities of GRaNIE.
I have obtained pan-cancer bulk RNA-seq data, which includes more than 10,000 samples and over 10,000 genes. These samples cover various cancer types, such as ACC, AML, BLCA, and many more. Additionally, I have acquired pan-cancer bulk ATAC-seq data, consisting of more than 800 samples and over 10,000 sequences, including cancer types like ACC and BLCA.
While these two datasets originate from different sets of samples, they share similar cancer types. My intention is to incorporate them into a Gene Regulatory Network (GRN) by representing them based on cancer classifications rather than individual samples.
The challenge I'm facing currently is that there are multiple samples belonging to the same cancer type. To integrate them into the GRN, I need to aggregate multiple samples into a single representative sample for each cancer type. I'm seeking guidance on how to effectively perform this aggregation process. Do you have any suggestions or recommendations for this task?
Thank you for your time and for developing the invaluable GRaNIE package. I appreciate any insights you can provide.
Best regards, [Chen Xiaoyong]