Stage-wise adjusted p-values for the confirmation hypothesis equal to 0

[iaradsouza1]

Hi,

Thank you very much for this tool! I'm using the stageR package to correct gene-wise multiple hypothesis testing for transcripts in a DTE analysis. One thing that is bothering me is that many of the transcript-adjusted p-values obtained with the getAdjustedPValues function are equal to 0. Is this a result of rounding really small p-values or do those zeros have another meaning?

[iaradsouza1]

I'm sorry, I just saw the same question on a closed issue here. If someone has the same doubt, please see this.