How to compare Seurat Log2FC with TradeSeq Log2FC
No2Ross opened this issue · 0 comments
No2Ross commented
Hi there.
I was just wondering how to compare the log2FC values between TradeSeq and a package like Seurat. I know Seurat's Log2FC is calculated by taking the row sums of the group genes, adding 1 then dividing by the mean and getting the log2 difference. How does this compare to TradeSeq's Log2FC? I have looked at the source code but I must confess i'm not sure how to intepret the code section for getting the Log2FC.
Thanks,
Ross