chromatin-interaction
There are 17 repositories under chromatin-interaction topic.
YaqiangCao/cLoops
Accurate and flexible loops calling tool for 3D genomic data.
YaqiangCao/cLoops2
Enhanced and elegant flexible peak/loop/domain -calling and analysis tool for 1D/3D genomic data.
aryeelab/hichipper
A preprocessing and QC pipeline for HiChIP data
bioinfomaticsCSU/LoopPredictor
LoopPredictor: Predicting unknown enhancer-mediated genome topology by an ensemble machine learning model
tzeitim/genome-blender
Scripts to create cartoons of 3D genomes
ibn-salem/sevenC
7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs
Linhua-Sun/Ath_Heat_Hi-C
Bioinformatic analysis of RNA-Seq, WGBS, and Hi-C in Arabidopsis
Pasquali-lab/UMI4Cats
An R package for analyzing UMI-4C chromatin contact data.
sirusb/R3CPET
3CPET: Finding Co-factor Complexes in Chia-PET experiment using a Hierarchical Dirichlet Process
Gabrielstav/mastercode
Code for my Master project
hanjunlee21/StructuralSimilarity
Identification of dynamic changes in chromatin conformation is a fundamental task in genetics. In 2020, Galan et al. presented CHESS (Comparison of Hi-C Experiments using Structural Similarity), a novel computational algorithm designed for systematic identification of structural differences in chromatin-contact maps. Using CHESS, the same group recently reported that chromatin organization is largely maintained across tissues during dorsoventral patterning of fruit fly embryos despite tissue-specific chromatin states and gene expression. However, here we show that the primary outputs of CHESS–namely, the structural similarity index (SSIM) profiles–are nearly identical regardless of the input matrices, even when query and reference reads were shuffled to destroy any significant differences. This issue stems from the dominance of the regional counting noise arising from stochastic sampling in chromatin-contact maps, reflecting a fundamentally incorrect assumption of the CHESS algorithm. Therefore, biological interpretation of SSIM profiles generated by CHESS requires considerable caution.
hanjunlee21/Lee-et-al-2023
RB represses cohesin-dependent loop formation and safeguards E2F-independent transcription
younglab/origami
Statistical Modeling of ChIA-PET interactions
yufanzhouonline/HiSIF
HiSIF: Genome-wide chromatin interactions identify characteristic promoter-distal loops