mutation-rate
There are 7 repositories under mutation-rate topic.
CaiLiLab/MuRaL
MuRaL is a deep learning framework for estimating single-nucleotide mutation rates across the genome.
j3551ca/BEAST-FLOW
Nextflow pipeline for estimation of evolutionary rate using Bayesian statistics.
0-Ioniel-0/guppy_MR
Repository for scripts used to estimate guppy (Poecilia reticulata) mutation rate.
rcs333/frequency-scanner
Reports frequency of all single nucleotide changes for a group of fastq files
tairsha/taxa-specific-substitution-matrix
Algorithms for the generation of substitution matrices from intra-taxa variation data. Implemented and published on human genetic variation data.
vmsatya/ConcurrentTherapySecondCancer
A biologically motivated mathematical formalism is used to estimate the relative risks of breast, lung and thyroid cancers in childhood cancer survivors due to concurrent therapy regimen. This model specifically includes possible organ-specific interaction between radiotherapy and chemotherapy. The model predicts relative risks for developing secondary cancers after chemotherapy in breast, lung and thyroid tissues, and compared with the epidemiological data.
vmsatya/SequentialTherapySecondCancer
We employed a biologically motivated mathematical model to estimate the radiation and chemotherapy-induced relative risks of thyroid malignancies in four childhood cancer study survivors (CCSS) data sets. the predictions of radiation and chemotherapy-induced relative risks of secondary thyroid malignancies using the mathematical model are compared against four clinical datasets from the CCSS cohort. Moreover, the extracted average value of growth rate of premalignant cells is 0.8175 (per day) and the extracted chemo-induced mutation rate is of the order of 10(−10) (per unit of chemotherapeutic dose).