pbpk
There are 207 repositories under pbpk topic.
Open-Systems-Pharmacology/Glucose-Insulin-Model
The physiologically-based whole-body model of the glucose-insulin-glucagon regulatory system
esqLABS/esqlabsR
Utility functions for modelling and simulation workflows within esqLABS organization
mhismail/ggdiagram
Create diagrams with ggplot.
Open-Systems-Pharmacology/Digoxin-Model
Whole-body PBPK model of digoxin as P-gp DDI victim drug
Open-Systems-Pharmacology/Pregnancy-Models
Physiologically Based Pharmacokinetic Models for Pregnant Women
Open-Systems-Pharmacology/Inhalation-model
Implementation of inhalation model in MoBi
Open-Systems-Pharmacology/Vancomycin-Model
Whole-body PBPK model of Vancomycin
GMPtk/RVis
Open access PBPK modelling platform
Open-Systems-Pharmacology/SGLT2i-hyperfiltration-model
A Quantitative Systems Pharmacology kidney model of diabetes associated renal hyperfiltration and the effects of SGLT inhibitors.
Open-Systems-Pharmacology/Thyroid-Hormones-PB-QSP-Model
Physiology-based systems pharmacology model of thyroid hormones regulation in rat and human
Open-Systems-Pharmacology/Voriconazole-Model
Whole-body PBPK model of voriconazole as CYP2C19 substrate and CYP3A4 perpetrator drug
insysbio/drug-loaded-nanoparticles
PBPK Modeling For Therapeutic Nanoparticles Loaded With Drug
Open-Systems-Pharmacology/Carbamazepine-Alprazolam-DDI
Modeling of published clinical Carbamazepine-Alprazolam-DDI studies for model evaluation
Open-Systems-Pharmacology/Carbamazepine-Efavirenz-DDI
Modeling of published clinical Carbamazepine-Efavirenz DDI studies for model evaluation
Open-Systems-Pharmacology/Carbamazepine-Midazolam-DDI
Modeling of published clinical Carbamazepine-Midazolam-DDI studies for model evaluation
Open-Systems-Pharmacology/Cimetidine-Alfentanil-DDI
Modeling of published clinical Cimetidine-Alfentanil-DDI studies for model evaluation
Open-Systems-Pharmacology/Cimetidine-Alprazolam-DDI
Modeling of published clinical Cimetidine-Alprazolam-DDI studies for model evaluation
Open-Systems-Pharmacology/Cimetidine-Carbamazepine-DDI
Modeling of published clinical Cimetidine-Carbamazepine DDI studies for model evaluation
Open-Systems-Pharmacology/Cimetidine-Model
Whole-body PBPK model of cimetidine (OCT2/MATE and CYP3A4 DDI perpetrator drug)
Open-Systems-Pharmacology/Cimetidine-Triazolam-DDI
Modeling of published clinical Cimetidine-Triazolam-DDI studies for model evaluation
Open-Systems-Pharmacology/Cimetidine-Verapamil-DDI
Modeling of published clinical Cimetidine-Verapamil-DDI studies for model evaluation
Open-Systems-Pharmacology/Erythromycin-Carbamazepine-DDI
Modeling of published clinical Erythromycin-Carbamazepine DDI studies for model evaluation
Open-Systems-Pharmacology/Levonorgestrel
Whole-body PBPK model of levonorgestrel with and without ethinyl estradiol as CYP3A4 DDI victim drug
Open-Systems-Pharmacology/Metoprolol-Model
PBPK model of metoprolol and metoprolol-CYP2D6 drug-gene interactions
Open-Systems-Pharmacology/Ritonavir-Model
PBPK model for ritonavir
xtalpi-xic/pk-model
Code for the paper "A Combination of Machine Learning and PBPK Modeling Approach for Pharmacokinetics Prediction of Small Molecules in Humans"