Installing PyMol.
Register PyMol with an Educational License
Links to the online AlphaFold implementations
BRAF FASTA sequence:
KTLGRDSDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQLQAFKNEVGVLRKTRHVNILFMGYSTKPQLAIVTQWCEGSLYHLHIETKFEMIKLIDIARQTAQGMDYLHAKSIHRDLKSNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINRDQIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKRDERPLFPQILASIELARSLPKIKIRPRGQRDSYWEIE
Important files are in the screening-docking folder and the CHARMM-GUI folder
Link to the docking/screening software, DockBlaster
The Zinc Database
Our ligand on the database
CD59 PDB structure
Membrane Lipids:
| Leaflet | Cholesterol | POPE | PSM |
|---|---|---|---|
| upper leaflet | 72 | 74 | 67 |
| lower leaflet | 73 | 75 | 68 |