Inferring disease-related microRNAs via PMDASNF
Just run 'PredSNFMDA_tool.m' to produce the result.
disease_semantic_s1.mat : disease semantic similarity 1(383×383)
disease_semantic_s2.mat : disease semantic similarity 2(383×383)
miRNA_function_s.mat ：microRNA functional similarity(495×495)
interaction.mat：microRNA-disease associations matrix(383×495)
disease number.xlsx : ID of all diseases
miRNA number.xlsx : ID of all microRNAs
PredSNFMDA_tool.m：main interface for running the program
gaussiansimilarity.m：calculate Gaussian interaction profile kernel similarity for microRNA and disease
SNF.m：fusion of multiple biological information networks
NCPMDA.m：calculate microRNA and disease space projection socres
Rank.m：sorting disease-related microRNAs scores
Write_file.m：write results to excel
software：matlab 2016a or later
processor：Intel(R) Xeon(R) CPU E5-1630 v4 @3.70GHz
recommended memory：8G