Hospital admissions linked to SARS-CoV-2 infection in children: a cohort study of 3.2 million first ascertained infections in England
Harrison Wilde, Christopher Tomlinson, Bilal A Mateen, David Selby, Hari Krishnan Kanthimathinathan, Padmanabhan Ramnarayan, Pascale Du Pre, Mae Johnson, Nazima Pathan, Arturo Gonzalez-Izquierdo, Alvina G Lai, Deepti Gurdasani, Christina Pagel, Spiros Denaxas, Sebastian Vollmer, Katherine Brown, On behalf of the CVD-COVID-UK/COVID-IMPACT consortium
We aim to describe the first occurrences of hospitalisations related to SARS-CoV-2 occurring amongst all first infections in the under-18 population in England. We use a hierarchical approach to categorise admissions according to their nature using input from a board of expert clinicians. These categories identify those admissions caused or contributed to by SARS-CoV-2 infection, versus admissions that were incidental to infection or nosocomial, splitting into interesting and significant sub-types where appropriate. Additionally, we explore the role and changing distributions of demographics, underlying health conditions and risk factors, and variant eras in these admissions.
Wilde H, Tomlinson C, Mateen B A, Selby D, Kanthimathinathan H K, Ramnarayan P et al. Hospital admissions linked to SARS-CoV-2 infection in children and adolescents: cohort study of 3.2 million first ascertained infections in England. BMJ 2023; 382:e073639 doi:10.1136/bmj-2022-073639
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This is a sub-project of project CCU029 approved by the CVD-COVID-UK / COVID-IMPACT Approvals & Oversight Board (sub-project: CCU029_01).
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