PySBOLGraph is a simple native Python library to read and write SBOL files, compatible with both Python 2.7 and Python 3.
Install using python setup.py install
The file crispr.py reproduces the CRISPR example that is also used in the tutorials for libSBOL, libSBOLj, sboljs and pysbol.
For a more powerful library with features such as automated sequence assembly, check out pysbol.