/oneSC

infer transcription factors circuits, simulate single cell expression trajectories

Primary LanguagePython

OneSC (One tool to Simulate Cells)

OneSC is a 2-in-1 computational tool that does two things:

  1. Infer a functional transcription factors circuit that describe cell state transitions in the single-cell expression data

  2. Simulate synthetic single-cell expression profiles that mimic cell state transitions using the core transcription factors circuit as regulatory backbone

You can read more about it in our preprint.

OneSC documentation is available through the link below.

Web documentation