Pinned Repositories
CapraLab.github.io
Capra Lab website
cosmis
COSMIS is a framework for quantifying the mutational constraint on amino acid sites in 3D spatial neighborhoods. The framework currently maps the landscape of 3D mutational constraint on 6.1 amino acid sites covering >80% (16,533) of human proteins.
cosmis_app
Dash based web application for interactive use of the COSMIS framework
DiGePred
Random Forest classifier designed to predict pairs of human genes capable to causing a digenic disease when carrying rare variants simultaneously. DiGePred has been trained using digenic pairs from DIDA and non-digenic pairs from unaffected relatives of individuals with rare undiagnosed disease.
lab-manuscript-template
An academic manuscript template with writing tips in both LaTeX and MS Word format generated by the Capra Lab (2/2022)
pdbmap
pipeline_download_scripts
BASH scripts to download required files for the psbadmin and pdbmap code
PSB
Personalized Structural Biology approach for rare coding variant interpretation, based on protein structural context and MD simulations.
resources
This directory includes useful tutorials and resources for working in the Capra lab.
VIPUR
A method for identifying deleterious protein variation.
Capra Lab's Repositories
CapraLab/cosmis
COSMIS is a framework for quantifying the mutational constraint on amino acid sites in 3D spatial neighborhoods. The framework currently maps the landscape of 3D mutational constraint on 6.1 amino acid sites covering >80% (16,533) of human proteins.
CapraLab/lab-manuscript-template
An academic manuscript template with writing tips in both LaTeX and MS Word format generated by the Capra Lab (2/2022)
CapraLab/DiGePred
Random Forest classifier designed to predict pairs of human genes capable to causing a digenic disease when carrying rare variants simultaneously. DiGePred has been trained using digenic pairs from DIDA and non-digenic pairs from unaffected relatives of individuals with rare undiagnosed disease.
CapraLab/pdbmap
CapraLab/pipeline_download_scripts
BASH scripts to download required files for the psbadmin and pdbmap code
CapraLab/resources
This directory includes useful tutorials and resources for working in the Capra lab.
CapraLab/CapraLab.github.io
Capra Lab website
CapraLab/cosmis_app
Dash based web application for interactive use of the COSMIS framework
CapraLab/PSB
Personalized Structural Biology approach for rare coding variant interpretation, based on protein structural context and MD simulations.
CapraLab/VIPUR
A method for identifying deleterious protein variation.