/MAN-1.0

An new version of MAN, which contains 8 kinds of biomolecules and 18 kinds of relationships.

MIT LicenseMIT

Molecular association network

Overview

Background: The explosive growth of genomic, chemical, and pathological data provides new opportunities and challenges for humans to thoroughly understand life activities in cells. However, there exist few computational models that aggregate various bioentities to comprehensively reveal the physical and functional landscape of biological systems.

Results: We constructed a molecular association network, which contains 18 edges (relationships) between 8 nodes (bioentities).

Doc

The edges and nodes can be found in the above files.

Reference:

If you find the data is useful for your research, please consider citing the following paper:

[3] Guo, Z. H., You, Z. H., Wang, Y. B., Huang, D. S., Yi, H. C., & Chen, Z. H. (2020). Bioentity2vec: Attribute-and behavior-driven representation for predicting multi-type relationships between bioentities. GigaScience, 9(6), giaa032. [2] Guo, Z. H., You, Z. H., Huang, D. S., Yi, H. C., Chen, Z. H., & Wang, Y. B. (2020). A learning based framework for diverse biomolecule relationship prediction in molecular association network. Communications biology, 3(1), 118.
[1] Guo, Z. H., You, Z. H., & Yi, H. C. (2020). Integrative construction and analysis of molecular association network in human cells by fusing node attribute and behavior information. Molecular Therapy-Nucleic Acids, 19, 498-506.