Transcription factor binding site atlas: A case study in reproducible big data science

  • getting_started - This getting_started shows how to access the footprint databases and provides a case example for query.

  • Followings are the supplementary information that these directories contains workflows and scripts used to generate DNase footprint, TF binding motif, and database.

    • generate_footprints - This generate_footprints provide an instruction for how to run the DNAse footprinting workflow and include a demo snapshot.

    • generate_motif - This generate_motif directory is a guideline if one needs to create transcription factor motifs. The motif file is used for annotating the footprints.

    • generate_db - The generate_db directory shows a step-by-step procedure along with the processing code to intersect hint or wellington] footprints output with the FIMO database and put the results in a database.