What is this?
In this repo you will find a bundle of data, code and notebooks for reproducibly generating and showcasing the analyses applied to solve a specific data science case (DSC).
Why is this here?
Learning and training – feel free to clone and re-run the analysis and suggest how it could be improved :)
I will update it incrementally as my own skills and knowledge develop.
About the Case We are tasked to analyse (within 2 weeks) processed ATAC-Seq and RNA-Seq datasets derived from an experiment comparing treatment vs control. All we know about the context is that the treatment group is thought to activate a transcriptional program via remodelling of the chromatin structure.
Aims
- Identify genes that may be regulated in this fashion.
- Identify the possible transcriptional programs involved.
- Present candidate transcription factors that may be responsible for the underlying regulation.
Note: This commit represents the bundle as it was delivered for assessment after 2 weeks work (21/10/2019).