moire
is a package implementing an MCMC based approach to estimating
complexity of infection (COI), also sometimes referred to as
multiplicity of infection (MOI), population allele frequencies, and
within-host relatedness from polyallelic genomics data.
moire
can be installed either using our r-universe repository
(preferred)
# Install from r-universe
install.packages("moire", repos = c("https://eppicenter.r-universe.dev", "https://cloud.r-project.org"))
or from GitHub using remotes
# Install development version from Github
remotes::install_github("EPPIcenter/moire")
moire supports loading data from either a long format data.frame
using
load_long_form_data()
or from a wide format data.frame
using
load_delimited_data()
.
df <- read.csv("your_data.csv")
data <- load_long_form_data(df)
# With data in appropriate format, run MCMC as follows
mcmc_results <- moire::run_mcmc(data, is_missing = data$is_missing)
The paper describing our method may be found here