GeoffChurch/unanimity

Consensus library and applications

Unanimity

C++ library and its applications to generate and process accurate consensus sequences

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Documentation

• Getting Started
• Projects
  • Available
    • Consensus Core
    • Circular Consensus Calling ccs
  • Work in Progress
    • Genomic Consensus Calling gcpp
    • Viral Haplotype Phasing eden
  • Planned
    • Minor Variant Calling
• Developer environment
• PacBio open source license

Quick Tools Overview

Circular Consensus Calling

ccs takes multiple reads of the same SMRTbell sequence and combines them, employing a statistical model, to produce one high quality consensus sequence.

Genomic Consensus Calling

gcpp will replace the current python GenomicConsensus, until then please use the existing solution.

Minor Variant Calling

This tool will be able to precisely call single-nucleotide variants from consensus data.

Viral Haplotype Phasing

eden will leverage CCS reads to identify low-frequency haplotypes within polyploid samples.

Help

Support is only provided for official and stable SMRT Analysis builds provided by PacBio and not for source builds.