Pinned Repositories
DayDayUp
dotfiles
My configuration files on MacOS.
DTI
FindCommon_NCBI
images_public
MASED
It's my graduation project at NJU with the help of professor WangQ.
perbool
A toolkit created for some bioinformatics work.
prepare_2018
configuration on Ubuntu 14.04.5LTS
withncbi
egaz and alignDB work with external (NCBI/EBI) data
WLog
Some (original or reposted) blogs.
IvanWoo22's Repositories
IvanWoo22/perbool
A toolkit created for some bioinformatics work.
IvanWoo22/DayDayUp
IvanWoo22/dotfiles
My configuration files on MacOS.
IvanWoo22/DTI
IvanWoo22/FindCommon_NCBI
IvanWoo22/images_public
IvanWoo22/IvanWoo22
IvanWoo22/MASED
It's my graduation project at NJU with the help of professor WangQ.
IvanWoo22/prepare_2018
configuration on Ubuntu 14.04.5LTS
IvanWoo22/withncbi
egaz and alignDB work with external (NCBI/EBI) data
IvanWoo22/WLog
Some (original or reposted) blogs.
IvanWoo22/NJU_seq
A brand new version of MgR_seq.
IvanWoo22/NJU_seq_open
IvanWoo22/prepare18.04
IvanWoo22/RNase_R_structure_prediction
RNase R is a member of the RNA exonuclease family that digests RNA from 3′ to 5′. Previous studies have identified RNase R from Mycoplasma genitalium (MgR) as its only RNA exonuclease, which is sensitive to Nm modification. However, the mechanism of this characteristic is not well understood. In this study, we aimed to explore the molecular mechanism of RNase R Nm sensitivity with the help of a newly established quantitative assay, which excluded the effect of hydrolytic activity. By comparing five wild-type RNase R from Mycoplasma, we indicated the importance of loop 18 in Nm sensitivity. Furthermore, we demonstrated the critical roles of L283, T278, and T279. This study deepened the molecular mechanism of the Nm sensitivity of MgR and provided the potential direction of protein engineering for application.
IvanWoo22/SD_benchmarking
Try different ways to identify segmental duplications.
IvanWoo22/SpliceSeq_Usage
IvanWoo22/Ubuntu21-04
My config on APHID.