# overreact
## Dependencies:
1. Reactome mapping file: Ensembl2Reactome.txt
```wget http://www.reactome.org/download/current/Ensembl2Reactome.txt
2. Running neo4j database with default settings (version 3.1)
Information available at http://www.reactome.org/pages/download-data/
under Graph Database. First, import the data by copying and pasting the
extracted tarball into the proper directory in your neo4j install. Then,
start the console.
3. Python bindings for neo4j
```pip install neo4j-driver
## Example usage:
knownlist.txt - a list of ensembl names (~10) which are known to be
associated with a particular phenotype, line-separated.
unknownlist.txt - a list of ensembl names (~100) which are randomly
selected, line-separated.
```python cross.py Ensembl2Reactome.txt knownlist.txt unknownlist.txt