Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates
Link to paper: 10.1016/j.biotechadv.2022.107947
Figure. To address the question of how yeast can be engineered for improved tolerance towards lignocellulosic hydrolysates, we have collected and statistically analysed the available data in literature. A meta-analysis of existing work on genetic alterations (gene deletion or overexpression) for tolerance towards individual inhibitors in lignocellulosic hydrolysates or to a hydrolysate as such was performed. UpSet plots represents the number of genes characterized in medium supplemented with different inhibitors or hydrolysates that resulted in a phenotypic change (sensitivity or tolerance towards the inhibitor), and the intersection among different sets.
This repository contains supplementary data and results that accompany the study in the respective 'data' and 'results' folders. Supplementary Figure 1 is located in the 'docs' folder.