/Isoform_Comparison

Comparison of Isoform Switching Events in 3 PanCancer Studies

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Comparison of Isoform Switching Events in 3 Pan-Cancer Studies

Comparison of overlapping Genes, Normal Isoforms, Cancer Isoforms and Normal:Cancer Isoform Switching Events across different cancer Types in the following published datasets:

  1. Vitting-Seerup, K., & Sandelin, A. (2017). The Landscape of Isoform Switches in Human Cancers. Molecular Cancer Research : MCR, 15(9), 1206–1220. http://doi.org/10.1158/1541-7786.MCR-16-0459

  2. Climente-González, H., Porta-Pardo, E., Godzik, A., & Eyras, E. (2017). The Functional Impact of Alternative Splicing in Cancer. Cell Reports, 20(9), 2215–2226. http://doi.org/10.1016/j.celrep.2017.08.012

  3. Kahraman, A., Karakulak, T., Szklarczyk, D., von Mering, C. (2020). Pathogenic impact of transcript isoform switching in 1,209 cancer samples covering 27 cancer types using an isoform-specific interaction network, Sci Rep 10, 14453 (2020). https://doi.org/10.1038/s41598-020-71221-5