TME_Microbiota
Multi-omics integration reveals the crucial role of Fusobacterium on the inflammatory immune microenvironment in head and neck squamous cell carcinoma
Context:
Rcode: R scripts used to reproduce all statistical results and visualized pictures.
Figure 1. Distinct microbial diversity and composition exhibit within various cancer types.
Figure 2. Cluster classification of immune characteristics can distinguish the prognosis of HNSC.
Figure 3. Fusobacterium enrichment correlates with an microenvironment of high inflammatory infiltration in HNSC.
Figure 4. Mutation landscape of microbiota-associated inflammatory genes in HNSC.
Figure 5. The interaction between microbiota and inflammatory immune microenvironment involves in LINC00707-miR539-EREG axis and chromatin accessibility.
Data Availability:
Rdata: The processing data used to reproduce all statistical results and visualized pictures.
For any other code/analysis inquiries, please open a github issue.