/fMRI_fsl

apply Full Analysis on FLANKER Dataset & Mapping brain regions using fsl and Unix commands.

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fMRI_fsl

Apply Full Analysis on FLANKER Dataset & Mapping brain regions using fsl and Unix commands.

To Download FLANKER dataset , Kindly click Here

Note that all tasks were part of the Health informatics course which was an fMRI based course in the 2nd semester of the 3rd year at Biomedical Engineering Department, Cairo University under the supervision of Dr.Meena Makary

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Contents:


Brief description:

1) QC-Task :

Check for MRI Artifacts and Motion correction for all 26 Subjects.

Click for steps 😄

2) Preprocessing-Task :

Apply Skull stripping / Feat time corrections / ETC to manually preprocess your subject data.

Click for steps 😄

Filtered image alt text
Skull striped image alt text

3) GLM-Task :

Manually apply General Linear Model on your data.

Click for steps 😄

Example GLM Design Z-stat
Sub-1

4) Neuroanatomy-Task :

Examine brain region cortical&sub-cortical with Harvard-Oxford brain strctural atlas.

Click for steps 😄

Region Example Image
Cortical Frontal Medial Cortex Frontal Medial Cortex
Sub-cortical Right Thalamus Right Thalamus

5) Scripting 1st Level Analysis :

Automatically perform 1st level analysis on all 26 FLANKER dataset subjects using Unix commands.

Click for steps OR Watch this Tutorial 📺

Credit for the Script: andrewjahn 🙌

6) Higher Level Analysis:

perform 2nd&3rd Level Analysis on the FLANKER dataset to obtain the segnificant clusters.

Click for steps 😄

A) 2nd Level Analysis

Design matrix for 2nd level analysis
EV Contrast

B) 3rd Level Analysis

Design matrix for 3rd level analysis
EV

Significant clusters in cope3

Region screenshot
1) 52% inasular cortex & 29% Frontal Orbital Cortex
2) 66% Lateral Occipital Cortex, inferior division & 10% Occipital Pole
3) 81% Paracingulate Gyrus & 7% Cingulate Gyrus,anterior division
4) 22% Precentral Gyrus & 12% Inferior Frontal Gyrus, pars opercularis
5) 79% Lateral Occipital Cortex, inferior division
6) 87% Lateral Occipital Cortex, inferior division
7) 49% Lateral Occipital Cortex, superior division

6) ROI Analysis:

apply region of interest analysis with anatomical & spherical approaches

Click for steps 😄

Anatomic Mask ROI

Region Screenshot t-test
Paracingulate Gyrus
Right amygdala

Spherical ROI

Region Screenshot Bar chart t-test
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