The goal of CIBERSORT is to run the CIBERSORT flow.
You can install the released version of CIBERSORT from github with:
install.packages("devtools")
devtools::install_github("Moonerss/CIBERSORT")
library(CIBERSORT)
sig_matrix <- system.file("extdata", "LM22.txt", package = "CIBERSORT")
mixture_file <- system.file("extdata", "exampleForLUAD.txt", package = "CIBERSORT")
results <- cibersort(sig_matrix, mixture_file)