/TheHumanPangenome

A Strategy for Building and Using a Human Reference Pangenome

Primary LanguageJupyter NotebookMIT LicenseMIT

TheHumanPangenome -- Creation of and Toolsets for Human Pangenomic Analysis

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The path of GRCh38 through a graph! For details check the DS folder!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/DS

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A Faster, Better Short-Read Mapper with Hit Chaining. Now with more corn! See the Giraffe folder for details!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/Giraffe

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Most Genome Annotations can be Imported from gff3 (to ggff!) quite easily! See the annotation folder for details!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/annotation

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Allele-Specific Expression can be calculated in a lightweight fashion! Grab the workflow in the RNA folder!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/RNA

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Calculate Mutations In, Outside of, and at Breakpoints of Structural Variants! See the SV folder for Details!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/SV/HG002

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We Mapped the MHC Region of HG002 to a Graph with Long Reads, Long Reads, 10X and love. Check out the MHC folder!

https://github.com/NCBI-Hackathons/TheHumanPangenome/tree/master/MHC