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Collect Installation Files
Latest EXE-Installer: https://get.adobe.com/de/reader/enterprise/ Latest MSP Updates: https://www.adobe.com/devnet-docs/acrobatetk/tools/ReleaseNotesDC/index.html
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Extract EXE File with 7-Zip
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Run an admin install of the Enterprise installer extracted MSI.
msiexec /a "extractedDirectory\AcroRead.msi" TARGETDIR="\\contoso.de\NETLOGON\acroread\new"
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Run an admin install with a patch option specifying the MSP on the Admin install you created in step 3.
msiexec /a \\contoso.de\NETLOGON\acroread\new\AcroRead.msi /update AcroRdrDCUpd2200120142.msp
NOW ADOBE INSTALLER WILL SLIPSTREAM THE MSP UPDATES TO THE MENTIONED MSI DEPLOY "\contoso.de\NETLOGON\acroread\new\AcroRead.msi" in GPO