Open-Systems-Pharmacology/PK-Sim
PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling
C#NOASSERTION
Pinned issues
Issues
- 1
Unable to create "Parameter Identification"
#2914 opened by siddhivernekar - 1
- 1
- 3
Migrate to .NET 8
#2905 opened by PavelBal - 0
Update PK-Sim dependency resolver to .NET8
#2912 opened by rwmcintosh - 10
- 0
Investigate dependency between PKSim.Infrastructure and OSPSuite.Presentation.Serialization
#2911 opened by rwmcintosh - 2
Add metabolizing enzyme MonoAminoOxydase A
#2907 opened by abderrahmanemeslouh - 2
Project conversion - cannot run the Aciclovir model
#2871 opened by PavelBal - 0
Save to snapshot: select simulations
#2904 opened by PavelBal - 0
Save to Snapshot: show a progress bar
#2903 opened by PavelBal - 0
Input parameters
#2902 opened by siddhivernekar - 0
Something went wrong
#2901 opened by nyxgy18 - 1
"Effective molecular weight" can become negative.
#2900 opened by PavelBal - 0
Adding Expression DB?
#2899 opened by cbruno14 - 0
Question: Basolateral mucosa permeability (P (interstitial->intracellular) , P (intracellular- >interstitial)) not in parameter identification
#2898 opened by michielve - 0
PK- Analysis report not loading to Excel
#2897 opened by siddhivernekar - 0
Commit ID included in version strings
#2887 opened by rwmcintosh - 10
PK sim file shows error after opening
#2894 opened by siddhivernekar - 0
PKSim suddenly closed by itself and gave an error message when I tried to reopen the file. Is there any way to retrieve the file?
#2893 opened by wwwendywww - 0
Observed data mapping lost when exchanging individual in simulation clone/configure
#2891 opened by Yuri05 - 0
Cannot download compound template
#2890 opened by gulugululee - 0
compound template could not be loaded
#2889 opened by gulugululee - 1
Code coverage does not work anymore
#2866 opened by Yuri05 - 8
After change in compound file by adding a clearance or removing and replace I have frequently this bug.
#2884 opened by hanssmit777 - 10
Allow / enable multiple formulations per a single Advanced Administration Protocol
#2883 opened by StephanSchaller - 0
Parameter view - make "Advanced" the default view
#2881 opened by PavelBal - 0
- 0
- 3
Having issues on single dosing administration on day 7
#2877 opened by shbae1211 - 1
PK-Analysis did not work
#2878 opened by shbae1211 - 6
- 7
Unit of t1/2 in individual enzyme expression is not updated when changing unit in Expression profile
#2847 opened by TWendl - 1
- 0
- 0
Show the Run# in the "Value Origin" for values obtained from a Parameter Estimation
#2873 opened by luisdavidj - 1
Prevent PK-Sim from including end stage renal disease patients in a normal population
#2868 opened by AndreDlm - 1
- 0
Modeling irreversible binding in PKSim /MoBi
#2864 opened by zt1947 - 0
- 2
Changes of gastric pH return to basal value too fast
#2855 opened by PavelBal - 2
Example projects
#2860 opened by zt1947 - 0
Example projects
#2861 opened by zt1947 - 0
An error occurred when I tried saving a project
#2859 opened by zt1947 - 0
Feature request: Add option to change expression profile used for a protein in individual
#2857 opened by AndreDlm - 3
PK-Sim database: unnecessary foreign key?
#2856 opened by Yuri05 - 0
- 1
- 0
Unnecessary warnings if simulation creation fails
#2853 opened by Yuri05 - 0
Cannot open an existing project
#2848 opened by carrot814