Incomplete equations for mixed inhibition and induction in the documentation
DeniTue opened this issue · 0 comments
DeniTue commented
Dear OSP-developers,
I checked for different equations defining inhibition and induction processes in the OSP documentation.
https://docs.open-systems-pharmacology.org/working-with-pk-sim/pk-sim-documentation/pk-sim-compounds-defining-inhibition-induction-processes#mixed-inhibition-simple-setting-with-one-inhibitor
For Mixed Inhibition, the equation describing KM,app seems to be incomplete and " * KM" is missing on the right side of the equation. The given equation describes the KM_interaction_factor and not KM,app.
For Enyzme Induction, the equation is missing at the end of the section and it would be appreciated, if this could be added here.
Thank you in advance.
Best regards,
Denise