/neutrophilCount

Computational pipeline to estimate neutrophil counts

Primary LanguageJupyter Notebook

This repository provides code for a research project using Boolean algorithms to identify genes associated with with neutrophil counts.

Here is a brief summary of the files included:

  • Neutrophil Analysis.ipynb: Notebook containing analysis and code to reproduce figures
  • ViolinPlot.py: library for generating specialized plots
  • neuAnalysis.py: script to load datasets used and analyze gene expression data (microarray and RNA-sequencing)
  • percentile.cpp: efficiently calculate percentile expression scores for a gene

To run the code, please install our lab softwares Hegemon and BoNE. The datasets analyzed can also be explored online in our database of over 30 neutrophil datasets.

A manuscript is under preparation and this computational analysis was used for a Curebound grant currently under review.