Does PECA work for uncommon animal species?
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Hi,
I read this paper "Modeling gene regulation from paired expression and chromatin accessibility data" and found this software will be very helpful for my research. My research organism is Amphimedon queenslandica (one kind of demosponge). I have the ATAC-Seq data and RNA-seq data. We have the genome and genome feature formate files. I want to know how could I use PECA for my analysis? I found this software only build in human and mm information.
Thanks for any useful information advance.
Best Regards
Huifang
Hi,
I read this paper "Modeling gene regulation from paired expression and chromatin accessibility data" and found this software will be very helpful for my research. My research organism is Amphimedon queenslandica (one kind of demosponge). I have the ATAC-Seq data and RNA-seq data. We have the genome and genome feature formate files. I want to know how could I use PECA for my analysis? I found this software only build in human and mm information.
Thanks for any useful information advance.Best Regards
Huifang
The current version of the software is just designed for human and mouse. But the method could be used in other species. To apply this method, you need to construct a prior of RE-TG first. Once this prior is available, we can use the PECA method. In the future version, we will consider to include other species.