Pinned Repositories
DurenLab
Duren Lab website
enrichTF
GenLouvain
A generalized Louvain method for community detection implemented in MATLAB
MACS
MACS -- Model-based Analysis of ChIP-Seq
matlab
PackageTry
PackageTry test
PECA
PECA is a software for inferring context specific gene regulatory network from paired gene expression and chromatin accessibility data
PECA-1
PECA is a software for inferring context specific gene regulatory network from paired gene expression and chromatin accessibility data
sc-compReg_matlab
scGEAToolbox
scGEAToolbox: Matlab toolbox for single-cell gene expression analyses
durenzn's Repositories
durenzn/PECA
PECA is a software for inferring context specific gene regulatory network from paired gene expression and chromatin accessibility data
durenzn/enrichTF
durenzn/DurenLab
Duren Lab website
durenzn/GenLouvain
A generalized Louvain method for community detection implemented in MATLAB
durenzn/MACS
MACS -- Model-based Analysis of ChIP-Seq
durenzn/matlab
durenzn/PackageTry
PackageTry test
durenzn/PECA-1
PECA is a software for inferring context specific gene regulatory network from paired gene expression and chromatin accessibility data
durenzn/sc-compReg_matlab
durenzn/scGEAToolbox
scGEAToolbox: Matlab toolbox for single-cell gene expression analyses
durenzn/spanonmf
An algorithm for low-dimensional ONMF and multi-component NN-PCA
durenzn/symnmf
Symmetric NMF for graph clustering
durenzn/Test
durenzn/TF-activity-network
To study systems-level properties of the cell, it is necessary to go beyond individual regulators and target genes to study the regulatory network among transcription factors (TFs). However, it is difficult to directly measure TF activity or DNA-binding fraction of TF by experiment. Here, we proposed a hierarchical graphical model to estimate TF activity from mRNA expression by building TF complexes with protein co-factors and inferring TF’s downstream regulatory network simultaneously.