Supplemental Materials for poster "A Simulator to Inform Alzheimer’s Disease and Dementia Trial Design" Presented at the virtual Society for Epidemiologic Research Conference on December 16, 2020. Funding for this research was provided by The United States’ National Institute on Aging grant 5R01AG057869-03, and is the work of Scott C. Zimmerman (1), Kaitlin Swinnerton (1), Camilla Calmasini (1), Melinda C. Power (2), Teresa Filshtein (3), Sarah F. Ackley (1), Megha L. Mehrotra (1), Jingkai Wei (2), Kan Z Gianattasio (2), Audra L. Gold (1), and M. Maria Glymour (1). 1: UCSF Dept of Epidemiology and Biostatistics, 2: George Washington University Dept of Epidemiology, 3: 23andMe.