Determination of product-growth-coupled strain designs employing stoichiometric metabolic models.
For an introduction to gcOpt, open and run "gcOpt_Example.m".
Usage of Matlab 2016b (https://de.mathworks.com/products/matlab.html) or later versions as well as the gurobi 7 (www.gurobi.com/) solver are recommended. COBRA toolbox is additionally needed (https://opencobra.github.io/cobratoolbox/stable/)
The content of this repository is licensed under a MIT License.
For a detailed description of the algorithm refer to the corresponding publication:
Determination of growth-coupling strategies and their underlying principles
Alter, T. B.; Ebert, B. E.
BMC Bioinformatics
https://doi.org/10.1186/s12859-019-2946-7