This is the repository related to our manuscript DepoScope: accurate phage depolymerase annotation and domain delineation using large language models, currently in submission at PLOS Computational Biology.
The easiest way to get started with DepoScope to predict depolymerases from your phage genomes or genes is to run the Google Colab that we provide here. You only need a zip file of your phage genomes to get started! Alternatively, go to the the scripts_clean folder and run the VII.DpoDetectionTool.ipynb notebook.
To run the benchmarking against other depolymerase detection tools, go to the benchmark folder and run the benchmark_notebook.ipynbnotebook.