QSAR modelling using Machine Learning gives understanding about Chemical and Biological structural relationship , biological activity of drug compounds.
In this QSAR based model development for Giloblastoma using Machine Learning approaches, the detailed work flow includes;
1 ) Downloading the data from :https://www.cancerrxgene.org/downloads/drug_data
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Filtering the data on the basis of log IC50 value
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Data preprocessing
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Descriptor Calculation using PADeL Software
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Feature Selection using Weka Software : https://sourceforge.net/projects/weka/
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Model Development