/MIMESIS

A package to identify type/subtype of tumor samples and estimate tumor content using minimal DNA-methylation signatures

Primary LanguageRMIT LicenseMIT

MIMESIS

MIMESIS is a computational workflow to quantify and classify tumor signals in tissue and cfDNA samples.

Citation

(accepted, waiting publication) Romagnoli, D. et al, 2023, MIMESIS: minimal DNA-methylation signatures to quantify and classify tumor signals in tissue and cell-free DNA samples. Briefings in Bioinformatics.

Installation

You can install the development version of MIMESIS from GitHub with:

# install.packages("devtools")
devtools::install_github("cgplab/MIMESIS")
devtools::install_github("cgplab/PAMES")

Example

library(MIMESIS)
library(PAMES)

## basic example code
samples_subtype <- classify_samples(bc_data)
samples_purity <- get_purity(bc_data, bc_sites)